{"id":105,"date":"2011-06-14T00:26:36","date_gmt":"2011-06-13T22:26:36","guid":{"rendered":"http:\/\/javierorlandi.com\/?p=105"},"modified":"2015-09-30T18:48:14","modified_gmt":"2015-09-30T16:48:14","slug":"unraveling-spontaneous-activity-in-neuronal-cultures","status":"publish","type":"post","link":"http:\/\/javierorlandi.com\/?p=105","title":{"rendered":"Unraveling Spontaneous Activity in Neuronal Cultures"},"content":{"rendered":"<p style=\"text-align: justify;\">Barcelona Computational and Systems Neuroscience (BARCCSYN) 2011<br \/>\nBarceona, Spain. 14-15 June <strong>2011<\/strong><\/p>\n<p style=\"text-align: justify;\"><b><!--more--><\/b><strong>Abstract:<\/strong><\/p>\n<p style=\"text-align: justify;\">Brain rhythms, retinal waves, epileptic seizures, Parkinsons tremors and many\u00a0other neurological processes share a common feature: they are driven by the\u00a0spontaneous activity of neuronal networks. And yet, the origins of this activity\u00a0remain poorly understood. In order to approach a quantitative understanding\u00a0of the common mechanisms that initiate and sustain spontaneous activity in\u00a0neuronal networks we focus our attention on neuronal cultures. Studying cultures both experimentally and theoretically we can unravel how spontaneous\u00a0activity can emerge and be maintained. In this talk we present new experimental evidence that verifies the hypothesis that spontaneous activity in cultures\u00a0is not a synchronous process. It is a localized process in which activity initiates in specific areas and propagates throughout the system. We also support\u00a0this claim with theoretical work that explains the physical processes that are\u00a0involved in the initiation of this activity. The internal structure of the network\u00a0that is obtained through the growth process of the culture is key to understand\u00a0how this spontaneous activity can emerge.<\/p>\n<p style=\"text-align: center;\" align=\"justify\">[\u00a0<a href=\"http:\/\/www.crm.cat\/en\/Activities\/Pages\/ActivityFoldersAndPages\/Curs%202011-2012\/BARCSYN2011\/default.aspx\">web<\/a> ]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Barcelona Computational and Systems Neuroscience (BARCCSYN) 2011 Barceona, Spain. 14-15 June 2011<\/p>\n","protected":false},"author":1,"featured_media":106,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[8],"tags":[],"_links":{"self":[{"href":"http:\/\/javierorlandi.com\/index.php?rest_route=\/wp\/v2\/posts\/105"}],"collection":[{"href":"http:\/\/javierorlandi.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/javierorlandi.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/javierorlandi.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/javierorlandi.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=105"}],"version-history":[{"count":5,"href":"http:\/\/javierorlandi.com\/index.php?rest_route=\/wp\/v2\/posts\/105\/revisions"}],"predecessor-version":[{"id":478,"href":"http:\/\/javierorlandi.com\/index.php?rest_route=\/wp\/v2\/posts\/105\/revisions\/478"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/javierorlandi.com\/index.php?rest_route=\/wp\/v2\/media\/106"}],"wp:attachment":[{"href":"http:\/\/javierorlandi.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=105"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/javierorlandi.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=105"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/javierorlandi.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=105"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}